Coat a 9- x 13-inch baking dish with cooking spray. Spread half of bread cubes in the dish.
Combine cream cheese, 1/3 cup maple syrup, vanilla, and orange rind. Spread mixture evenly over bread cubes with a spatula. Top with blueberries. Top blueberries with remaining bread cubes.
Combine eggs, milk, salt, and remaining maple syrup in a large bowl; stir well with whisk. Pour egg mixture evenly over bread layers, pressing lightly with a spatula to help the top layers absorb egg mixture. Cover with foil and chill overnight.
The next morning, preheat oven to 350°. Bake covered for 1 hour; remove foil and bake an additional 30 minutes. Allow to sit 10 minutes before cutting into.